Citizens reacted from the streets of Belgrade on Friday to news that Serbian tennis star Novak Djokovic's Australian visa had been cancelled for a second time over his COVID-19 vaccination status.

The Serbian world number one faces the possibility of deportation after Australian Immigration Minister Alex Hawke used his ministerial discretion to cancel Djokovic's visa on the grounds of "health and good order."

Residents of Belgrade expressed a range of opinions on the matter, with some leaping to Djokovic's defence.

"It's a pity they are harassing him so much. He is the number one in the world. We'll see what happens. I disagree with them (the Australian government)," said Miroljub, a resident of Belgrade.

Another resident, Miroslav, gave the opposite point of view saying that if Djokovic had failed to follow Australian regulations he should face the consequences.

"I heard he made a fraud of some sort and if he really did it, then he should be deported, it doesn't matter that he is number one in the world and that he won nine times trophy there," he said.

Djokovic is now expected to attend a meeting alongside his lawyers with Australian immigration officials on Saturday after which he is due to be detained. The Serbian star is expected to appeal the visa cancellation, following a successful challenge against an initial visa cancellation earlier this month.

The tennis star is in Australia hoping to defend his Australian Open title in Melbourne next week.